* Intro: popular drug Ozempic was FDA approved 2017 for diabetes which has semaglutide as the active ingredient. It is now used as “off label” for weight loss throughout the country.

* Mechanism of action: like hormone incretin so central fullness & slows gastric emptying

* Duration: weekly shot under skin of lower abdomen at our clinic or at home

* Results: Usual weight loss is 7-15% in 1 year. Goal is to lose 1-3 lbs per week

* Gastro side effects (5-15% of clients): nausea, vomiting, bloating, gas, abdominal pain, diarrhea, constipation

* CNS side effects: headache, dizziness, fatigue. Also hypoglycemia & hypotension.

* Dosages: first month .25mg then next month 0.5 mg > 1mg > 2mg (if necessary)

 * Costs: brand name Ozempic or Wegovy costs almost $500/month.  Mostly not insurance covered for weight loss.



GLP-2=Tirz > $225/ month for 2.5mg dose per week

COMPOUNDED PEPTIDE. BRAND NAME MOUNJARO, ZEPBOUND

Visit clinic weekly or take home monthly.

* Intro: popular drug Mounjaro was approved 2021 for diabetes & in 2023 for weight loss. Its active ingredient is tirzepatide.

* Mechanism of action, duration, results, side effects "similar" to semaglutide

* Difference: about 2x stronger than semaglutide for some clients but varies from person to person. Gastrointestinal side effects maybe more.

* First month start at 2.5mg, then next month 5 mg > then 7.5mg > then 10mg > then 12.5mg

* Costs: Mounjaro or Zepbound brand costs almost $500/month. Mostly not insurance covered for weight loss.